Cristian Romero, a standout for Tottenham, scored before getting hurt and having to leave right away.
Ange Postecoglou’s administration got off to a great start thanks to the Argentine, who gave Spurs the lead after just 11 minutes.
Romero headed in a James Maddison free-kick after attacking it; the goal stood despite a VAR offside check.
The center-back, though, went from hero to zero after being injured and replaced immediately after celebrating.
Romero was engaged in a head-on collision as he scored, leading Tottenham to remove him as a safety measure.
The 25-year-old was furious and refused to carry on playing.
Romero needed to be excused by Postecoglou and his teammates.
Davinson Sanchez, a forgotten man, took his spot.
After the two teams agreed on a £13 million transfer fee, the Colombian was prepared to join Spartak Moscow, but the player declined.
Despite having 205 appearances for Spurs, he only started eight Premier League games last season.
With goals from Yoane Wissa and Bryan Mbeumo, Brentford quickly regained control of the game.
After that, Emerson Royal scored from a distance to make it 2-2 as the teams entered the locker rooms.
That came after the game’s start was postponed because of a sanitary concern.